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“Great Things from Small Things” – The Next Industrial Revolution!

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“Nanotechnology – Great Things from Small Things”

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About Genesis Nanotechnology, Inc.

Genesis Nanotechnology, Inc. (GNT) is an Applied Nanotechnology IP Holding and Development Company. GNT acquires, holds and develops Patents & Trade Secrets & Processes, then markets those IP’s for Nanomaterials across a broad spectrum of mature Industry Markets. GNT creates ‘enterprise value’ & the opportunity for multiple revenue streams by obtaining the rights to & developing early stage ‘Nano-Intellectual Properties’ (NIP).

GNT is actively evaluating patented and emerging nanotechnology opportunities for Joint Venture and Strategic Alliances. GNT creates short and long term revenues, in addition to ‘enterprise value’ by:  Identifying, Developing, Integrating and then Commercializing, nanotechnologies that demonstrate significant new disruptive capabilities, enhance new or existing product performance and/or beneficially impact input cost reductions and efficiencies and therefore will achieve a sustainable and competitive advantage in their chosen market sector.

Market and Industry ApplicationsApplications-of-Nanomaterials-Chart-Picture1

 Applied Nanomaterials are being integrated into existing markets and are facilitating emerging products and technologies that are being developed by a very deep field of mature and financially capable companies: [Examples: Hitachi, Samsung, Siemens Lockheed Martin, 3M, DOW, NVC, Merck, Glaxo Smith-Kline]

Nano-Engineered Materials are impacting Medicine, Consumer Electronics, Energy Solutions and Advanced Fabrics. [Examples: Nano-Medicine, (Cancer Treatment Diagnostics, Drug Delivery & Therapy); Solid-State Lighting, Screen Displays (LED, LCD,QLED), Semi-Conductors, Security Inks, Paints, Coatings & Filters, QD Enabled Solar Cells, Ion-Lithium & Organic Batteries, Water Filtration & Desalinization, Military Armor and Identification and Natural Gas & Oil Market applications.]

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Do you have or do you know of a ‘Special Water Project’ that is looking for Partners and/ or Support? We are looking for ‘Partners & Projects” for our Funding Campaign. If you are aware of or involved in a special water project, please contact us via our Website’s ‘Contact Form’ at:

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Thank You! Genesis Nanotechnology – “Great Things from Small Things”

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Progress Review of the National Nanotechnology Initiative: Update


3D rendered Molecule (Abstract) with Clipping PathThis document provides an overview of progress on the implementation and coordination of the 2011 NNI Environmental, Health, and Safety (EHS) Research Strategy that was developed by the Nanoscale Science, Engineering, and Technology Subcommittee’s Nanotechnology Environmental and Health Implications (NEHI) Working Group.

 

Consistent with the adaptive management process described in this strategy, the NEHI Working Group has made significant progress through the use of various evaluation tools to understand the current status of nanotechnology-related EHS (nanoEHS) research and the Federal nanoEHS research investment.

Most notably, the participating agencies reported to the NEHI Working Group examples of ongoing, completed, and anticipated EHS research (from FY 2009 through FY 2012) relevant to implementation of the 2011 NNI EHS Research Strategy.

These examples, described in this document, demonstrate the breadth of activities in all six core research areas of the 2011 NNI EHS Research Strategy: Nanomaterial Measurement Infrastructure, Human Exposure Assessment, Human Health, Environment, Risk Assessment and Risk Management Methods, and Informatics and Modeling. Overall, coordination and implementation of the 2011 NNI EHS Strategy across the NEHI agencies has enabled:

  • Development of comprehensive measurement tools that consider the full life cycles of engineered nanomaterials (ENMs) in various media.
  • Collection of exposure assessment data and resources to inform workplace exposure control strategies for key classes of ENMs.
  • Enhanced understanding of the modes of interaction between ENMs and physiological systems relevant to human biology.
  • Improved assessment of transport and transformations of ENMs in various environmental media, biological systems, and over full life cycles.
  • Development of principles for establishing robust risk assessment and risk management practices for ENMs and nanotechnology-enabled products that incorporate ENMs, as well as approaches for identifying, characterizing, and communicating risks to all stakeholders.
  • Coordination of efforts to enhance data quality, modeling, and simulation capabilities for nanotechnology, towards building a collaborative nanoinformatics infrastructure.

Extensive collaboration and coordination among the NEHI agencies as well as with international organizations is evident by the numerous research examples and by other activities such as co-sponsored workshops and interagency agreements described in this review document. These examples and activities are a small subset of the extensive research efforts at the NEHI agencies. This document addresses the NEHI Working Group’s broader efforts in coordination, implementation, and social outreach in nanoEHS, as identified in the 2011 NNI EHS Research Strategy. As the NNI agencies sustain a robust budget for EHS research, Federal agencies will continue to invest in tools and share information essential to assess and manage potential risks of current and anticipated ENMs and nanotechnology-enabled products throughout their life cycles. The agencies will also continue to engage with the stakeholder community to establish a broad EHS knowledge base in support of regulatory decision making and responsible development of nanotechnology.

 

Nanotubes Seen as Alternative When Silicon Chips Hit Their Limits


By 
Published: February 19, 2013   Bits

Mega UploadsSAN FRANCISCO — In the next decade or so, the circuits etched on silicon-based computer chips are expected to shrink as small as they can physically become, prompting a search for alternative materials to take their place.

Some researchers are putting high hopes on carbon nanotubes, and on Monday a group of researchers at Stanford successfully demonstrated a simple microelectronic circuit composed of 44 transistors fabricated entirely from the threadlike fibers.

The development, which was presented both as a paper and a working demonstration at a technical conference here, is the most striking evidence yet that carbon nanotubes may prove to be the material of the future when today’s silicon-based chips reach their fundamental physical limits.

I.B.M., which is one of the biggest proponents of nanotubes for microelectronic applications, has made clear its hope that carbon nanotube technology will be ready a decade from now, when semiconductors are expected to shrink to minimum dimensions of just 5 nanometers. But until now, researchers at universities and chip makers have succeeded in making only individual devices, like transistors, from carbon nanotubes.

The Stanford development is the first time a complete working circuit has been created and publicly demonstrated, suggesting that the material may indeed live up to its promise.

Silicon, a plentiful natural element that functions both as a conductor and an insulator, has already lasted decades longer than computer engineers originally expected, as generations of increasingly smaller transistors have been perfected. It is used by the computer chip industry to etch circuits much finer than the wave length of light, and engineers and scientists say they believe that the material will continue to scale down, at least until the end of the decade.

But sooner or later the shrinking of circuits made from the material will stop, ending the microelectronic era that has been defined by Moore’s Law, the 1965 observation by the Intel co-founder Gordon Moore that the number of transistors that could be placed on a silicon chip doubled at regular intervals.

The Stanford advance seems to hold promise for the belief that whenever the silicon era stalls, the scaling-down process will continue, and permit designers to increase power and capacity of computers far into the future.

The Stanford demonstration came during a session at the International Solid State Circuits Conference, held here annually. A graduate student, Max Shulaker, chose a wooden, human-size hand, connected to a simple motor and gear arrangement on a makeshift stand. Onstage, he threw a switch and the hand shook vigorously.

It was a simple demonstration, but the research group said its goal was to build an entire microprocessor from carbon nanotubes to confirm the potential of the material.

Besides their small size, carbon nanotubes use much less power and switch faster than today’s silicon transistors.

“The bottom line is you can expect an order of magnitude in power saving at the system level,” said Subhasish Mitra, an associate professor of electrical engineering at Stanford and director of the Robust Systems Group. That offers tremendous promise for effectively increasing the battery life in mobile consumer devices in the future, he said.

Other new materials and variations of silicon-based transistors are also being studied to see if they will shrink to smaller sizes. Intel, for example, last year began using a three-dimensional transistor called a FinFET. By turning the device on its side, the chip maker was able to pack transistors more densely on the surface of a chip.

“I’m not saying there is nothing else around,” said H.-S. Philip Wong, a Stanford electrical engineering professor. “It’s just a matter of who wins when you scale down to really, really small dimensions.”

The challenge of carbon nanotubes in their type state is that they form a giant “hairball” of interwoven molecules. However, by chemically growing them on a quartz surface, the researchers are able to align them closely and in regularly spaced rows. They then transfer them to a silicon wafer, where they used conventional photolithographic techniques to make working circuits.

The technological hurdle has been to make reliable circuits even when a small percentage of the wires are misaligned. The Stanford group stated it had perfected a circuit technique that made use of redundancy to work around the imperfectly formed wires.

Dr. Mitra said that “99.5 percent looks very nice on a PowerPoint slide. But when you’re talking about 10 billion things, .5 percent of 10 billion is a really large number, and that completely messes things up.”

Beyond microelectronics, carbon nanotubes are showing promise in commercial applications like rechargeable batteries, bicycle frames, ship hulls, solar cells and water filters, according to an article in the Feb. 1 issue of the journal Science.

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A version of this article appeared in print on February 20, 2013, on page B4 of the New York edition with the headline: Nanotubes Seen as Alternative When Silicon Chips Hit Their Limits.

Derek Paravicini and Adam Ockelford: In the key of genius


imagesCAMR5BLR Einstein Judging a FishPublished on Aug  9, 2013

GNT writes: In a departure from all things small … we are truly amazed by this story. From the ‘human capacity to overcome’ perspective to the ‘backstory’ of the a-m-a-z-I-n-g capabilities of the body human … please enjoy and appreciate this truly amazing talent!  

 

Born three and a half months prematurely, Derek Paravicini is blind and has severe autism. But with perfect pitch, innate talent and a lot of practice, he became an acclaimed concert pianist by the age of 10. Here, his longtime piano teacher, Adam Ockelford, explains his student’s unique relationship to music, while Paravicini shows how he has ripped up the “Chopsticks” rule book. (Filmed at TEDxWarwick.)

 

 

 
TEDTalks is a daily video podcast of the best talks and performances from the TED Conference, where the world’s leading thinkers and doers give the talk of their lives in 18 minutes (or less). Look for talks on Technology, Entertainment and Design — plus science, business, global issues, the arts and much more.

 

Find closed captions and translated subtitles in many languages at http://www.ted.com/translate
Follow TED news on Twitter: http://www.twitter.com/tednews Like TED on Facebook: https://www.facebook.com/TED

 
Subscribe to our channel: http://www.youtube.com/user/TEDtalksD…

Nanoparticle Drug Delivery in Cancer Therapy


Published on Mar  3, 2013

http://youtu.be/emEua2eJp1U

 

QDOTS imagesCAKXSY1K 8

Follow our channel on Twitterhttps://twitter.com/Nanobotmodels
Read more in article: http://www.nanobotmodels.com/node/69
Nanobotmodels Company presents vision of modern drug delivery methods using  DNA-origami nanoparticles. In animation you can see cancer therapy using doxorubicin, delivered  by nanomedicine methods.

$244 BILLION in Renewable Energy Investments: 2012


Jun 14, 2013

REN21 Frankfort School - UNEP reports renewable energy investments globally
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Around $244 billion was invested in renewable energy in 2012, with a geographic shift toward developing countries, according to sister reports released by REN21, a global renewable energy policy network, and the Frankfurt School – UNEP Collaborating Centre for Climate & Sustainable Energy Finance.

According to the reports, 115 GW of new renewable capacity was installed globally in 2012, although global investments fell 12 percent from 2011. The drop in investment was mainly because of dramatically lower solar prices and weakened U.S. and European markets, according to the report from the Frankfurt School.

Despite that, 2012 remains the second highest year in history for renewable energy investments, with a continuing upward trend in developing companies. The reports note that investments in developing countries were around $112 billion, compared to $132 billion in developed countries.

The reports noted that renewable energy made up about half the total electric capacity addition in the U.S. in 2012, with more capacity added from wind power than any other technology. Total investment in renewable energy was down 34 percent to $36 billion, however. The reports cite uncertainties over U.S. policy as the main reason for the decrease in total renewable investment.

The largest investment in renewable energy was made in China, where a 22 percent increase raised the total investment in 2012 to $67 billion, largely due to a jump in solar investment, according to the reports.

Wind power accounted for about 39 percent of the renewable energy capacity added in 2012, followed by hydropower and solar photovoltaic power, which each accounted for about 26 percent of new capacity.

Renewable Energy: World Invests $244 billion in 2012, Geographic Shift to Developing Countries. Installed capacity continues to grow as solar prices drop 30-40%, new wind installations surge

For only the second time since 2006, global investments in renewable energy in 2012 failed to top the year before, falling 12% mainly due to dramatically lower solar prices and weakened US and EU markets.

There was a continuing upward trend in developing countries in 2012, with investments in the South topping $112 billion vs $132 billion in developed countries – a dramatic change from 2007, when developed economies invested 2.5 times more in renewables (excluding large hydro) than developing countries, a gap that has closed to just 18%.

The main issue holding back investment last year was instability in the policy regime for renewable energy in important developed-economy markets. Future investment is likely to coalesce in countries that can offer policies that command investor confidence, plus the need for extra generating capacity and strong renewable power resources.

After being neck-and-neck with the US in 2011, China was the dominant country in 2012 for investment in renewable energy, its commitments rising 22% to $67 billion, thanks to a jump in solar investment. But there were also sharp increases in investment for several other emerging economies, including South Africa, Morocco, Mexico, Chile and Kenya.

The other major theme of 2012 was a further, significant reduction in the costs of solar photovoltaic technology. The levelised cost of generating a MWh of electricity from PV was around one third lower last year than the 2011 average. This took small-scale residential PV power, in particular, much closer to competitiveness.

Wipe-On Nanocoating to Exceed Automotive OEM Specs


QDOTS imagesCAKXSY1K 8(Nanowerk News) Imagine for a moment a world were  automotive plastics never fade, a self-cleaning wheel that resists brake dust, a  self-cleaning tire that looks new for life, or a fiberglass boat that resists  fading for life. These and other amazing benefits are now possible due to 10  years of research & development in nanotechnology.
According to Nanovere Technologies Chairman & Chief  Technology Officer Thomas Choate, “Nanovere is pleased to introduce the world’s  first Wipe-On clear nanocoating to exceed automotive OEM specifications. The  product is named Vecdor Nano-Clear®. What’s most unique about Nano-Clear® is the  ability to permanently restore original color, gloss and surface hardness back  into oxidized textured plastics, highly oxidized fiberglass and highly oxidized  paint surfaces while reducing surface maintenance by 60%.”
Nanotechnology can be described as the science of molecular  engineering. Nanovere Technologies has pioneered proprietary 3D nanostructured  coatings at the molecular level since 2003. Nano-Clear® forms a “highly  crosslink dense film with extreme scratch resistance, chemical resistance, UV  resistance, remarkable flexibility and self-cleaning properties including water,  oil, ice and brake-dust repellency.”
The application potential for Nano-Clear® Wipe-On nanocoating  includes automotive textured plastics, aluminum and steel wheels, tires,  oxidized paint surfaces including heavy duty equipment, boat hulls, aluminum  siding, outdoor metal furniture, air conditioner housings, etc.
Vecdor nanocoatings have been tested and validated by some of  the world’s leading OEM companies including Boeing, BMW, Accuride Truck Wheels  and many others to outperform leading OEM clear coatings;
  • 53%  higher scratch resistance: 4H pencil hardness
  • 476%  higher chemical resistance over nearest competitor: 500+ MEK rubs
  • 60%  reduced surface maintenance: water, oil and ice repellency
  • 94%  gloss retention even after 5 years
Nanovere is currently establishing global distribution networks&nbsp; for Vecdor Nano-Clear®. Interested parties may contact Nanovere directly at&nbsp; alliances@nanovere.com or call us at&nbsp; (810)&nbsp; 227-0077 . To learn&nbsp; more about Nanovere or nanotechnology, please visit us at&nbsp; http://www.nanocoatings.com or email question@nanovere.com.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;
Nanovere Technologies, LLC. specializes in the research &  development of first-to-market nanocoatings and licensing of 3D nanostructured  coating polymers to a world leading paint manufacture. Nanovere Technologies was  founded in 2003 and invented the core polymers and nanocoatings which currently  represent 11 global patents pending.
Source: Nanovere (press  release)

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Nanoparticles Enable Earlier Cancer Diagnosis


QDOTS imagesCAKXSY1K 8 From Science Daily, Dec. 17, 2012 — Finding ways to diagnose cancer earlier could greatly improve the chances of survival for many patients. One way to do this is to look for specific proteins secreted by cancer cells, which circulate in the bloodstream. However, the quantity of these biomarkers is so low that detecting them has proven difficult.


 A new technology developed at MIT may help to make biomarker detection much easier. The researchers, led by Sangeeta Bhatia, have developed nanoparticles that can home to a tumor and interact with cancer proteins to produce thousands of biomarkers, which can then be easily detected in the patient’s urine.

This biomarker amplification system could also be used to monitor disease progression and track how tumors respond to treatment, says Bhatia, the John and Dorothy Wilson Professor of Health Sciences and Technology and Electrical Engineering and Computer Science at MIT.

“There’s a desperate search for biomarkers, for early detection or disease prognosis, or looking at how the body responds to therapy,” says Bhatia, who is also a member of MIT’s David H. Koch Institute for Integrative Cancer Research. She adds that the search has been complicated because genomic studies have revealed that many cancers, such as breast cancer, are actually groups of several diseases with different genetic signatures.

The MIT team, working with researchers from Beth Israel Deaconess Medical Center, described the new technology in a paper appearing in Nature Biotechnology on Dec. 16. Lead author of the paper is Gabriel Kwong, a postdoc in MIT’s Institute for Medical Engineering and Science and the Koch Institute.

Amplifying cancer signals

Cancer cells produce many proteins not found in healthy cells. However, these proteins are often so diluted in the bloodstream that they are nearly impossible to identify. A recent study from Stanford University researchers found that even using the best existing biomarkers for ovarian cancer, and the best technology to detect them, an ovarian tumor would not be found until eight to 10 years after it formed.

“The cell is making biomarkers, but it has limited production capacity,” Bhatia says. “That’s when we had this ‘aha’ moment: What if you could deliver something that could amplify that signal?”

Serendipitously, Bhatia’s lab was already working on nanoparticles that could be put to use detecting cancer biomarkers. Originally intended as imaging agents for tumors, the particles interact with enzymes known as proteases, which cleave proteins into smaller fragments.

Cancer cells often produce large quantities of proteases known as MMPs. These proteases help cancer cells escape their original locations and spread uncontrollably by cutting through proteins of the extracellular matrix, which normally holds cells in place.

The researchers coated their nanoparticles with peptides (short protein fragments) targeted by several of the MMP proteases. The treated nanoparticles accumulate at tumor sites, making their way through the leaky blood vessels that typically surround tumors. There, the proteases cleave hundreds of peptides from the nanoparticles, releasing them into the bloodstream.

The peptides rapidly accumulate in the kidneys and are excreted in the urine, where they can be detected using mass spectrometry.

This new system is an exciting approach to overcoming the problem of biomarker scarcity in the body, says Sanjiv Gambhir, chairman of the Department of Radiology at Stanford University School of Medicine. “Instead of being dependent on the body to naturally shed biomarkers, you’re sampling the site of interest and causing biomarkers that you engineered to be released,” says Gambhir, who was not part of the research team.

Distinctive signatures

To make the biomarker readings as precise as possible, the researchers designed their particles to express 10 different peptides, each of which is cleaved by a different one of the dozens of MMP proteases. Each of these peptides is a different size, making it possible to distinguish them with mass spectrometry. This should allow researchers to identify distinct signatures associated with different types of tumors.

In this study, the researchers tested their nanoparticles’ ability to detect the early stages of colorectal cancer in mice, and to monitor the progression of liver fibrosis.

Liver fibrosis is an accumulation of scarring in response to liver injury or chronic liver disease. Patients with this condition have to be regularly monitored by biopsy, which is expensive and invasive, to make sure they are getting the right treatment. In mice, the researchers found that the nanoparticles could offer much more rapid feedback than biopsies.

They also found that the nanoparticles could accurately reveal the early formation of colorectal tumors. In ongoing studies, the team is studying the particles’ ability to measure tumor response to chemotherapy and to detect metastasis.

The research was funded by the National Institutes of Health and the Kathy and Curt Marble Cancer Research Fund.

Oerlikon completes the sale of its solar segment to Tokyo Electron


(Nanowerk News) Oerlikon announces the closing of the  sale of its Solar business to Tokyo Electron Ltd. (TEL). The contract to divest  the Solar business was signed on March 2, 2012. The transaction was structured  as a cash deal in which TEL acquires 100 % of the shares of Oerlikon Solar and  closed in line with the original expectations of the signed agreement resulting  in cash proceeds for Oerlikon amounting to CHF 250 million.

“The closing of this transaction marks another important step in  the optimization of our business portfolio. TEL, as a strategic buyer and  leading supplier of semiconductor production equipment, is well suited to  utilize the advantages of the thin film silicon solar technology in a  sustainable and successful manner”, said Dr. Michael Buscher, CEO of the  Oerlikon Group.

Hiroshi Takenaka, President and CEO of TEL, commented, “We can  look forward to further growth in demand for thin-film silicon photovoltaic  panels, particularly for large-scale power generation, as a result of their  superiority in actual energy generation in regions with abundant sunlight and  the cost advantages. Oerlikon Solar has world-leading technology in this field  relating to conversion efficiency and manufacturing costs. By combining its  technologies with the advanced technologies that TEL has nurtured in the  semiconductor production equipment business, we will be able to develop more  competitive devices. This acquisition is an undertaking intended to establish  the photovoltaic panel (PV) production equipment business as a new core business  that will support TEL’s growth strategy.”

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Improved nanoparticles deliver drugs into brain


Written by Hopkins CCNE    Friday, 09 November 2012 09:12
brain
Researchers report they are one step closer to a drug-delivery system flexible enough to overcome some key challenges posed by brain cancer and other maladies affecting the brain.

In a report published in Science Translational Medicine, a team of researchers from Johns Hopkins says it has designed nanoparticles that can safely and predictably infiltrate deep into the brain when tested in rodent and human tissue. “We are pleased to have found a way to prevent drug-embedded particles from sticking to their surroundings so that they can spread once they are in the brain,” says Justin Hanes, a project leader at the Hopkins CCNE and director of the Johns Hopkins Center for Nanomedicine.

After surgery to remove a brain tumor, standard treatment protocols include the administering chemotherapy directly to the surgical site to kill any cells left behind that could not be surgically removed. To date, this method of preventing tumor recurrence is only moderately successful, in part because it is hard to administer a dose of chemotherapy high enough to sufficiently penetrate the tissue to be effective and low enough to be safe for the patient and healthy tissue.

To overcome this dosage challenge, Dr. Hanes and his colleagues designed nanoparticles that are able to travel faster and further into the brain tissue. While conventional drug-delivery nanoparticles typically stick to cells at the application site and tend to not migrate deeper into the brain, these new nanoparticles, coated with a dense layer of poly(ethylene glycol (PEG)interact minimally with the surrounding tissue and are more able to move out from the injection site.

To test the performance of their slippery nanoparticles, Dr. Hanes and his colleagues injected the coated beads into slices of rodent and human brain tissue. They first labeled the beads with glowing tags that enabled them to see the beads as they moved through the tissue. Compared to non-PEG-coated beads, or beads with a less dense PEG coating, they found that a dense coating of PEG allowed larger beads to penetrate the tissue, even those beads that were nearly twice the size previously thought to be the maximum possible for penetration within the brain. They then tested these beads in live rodent brains and found the same results.

The researchers then took biodegradable nanoparticles carrying the chemotherapy drug paclitaxel, and coated them with PEG. As expected, in rat brain tissue, nanoparticles without the PEG coating moved very little, while PEG-covered nanoparticles distributed themselves quite well.

This work, which is detailed in a paper titled, “A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue,” was supported in part by the NCI Alliance for Nanotechnology in Cancer, a comprehensive initiative designed to accelerate the application of nanotechnology to the prevention, diagnosis, and treatment of cancer. An abstract of this paper is available at the journal’s website.

See: http://nano.cancer.gov/action/news/2012/oct/nanotech_news_2012-10-16a.asp?goback=.gde_3287601_member_176789619