Nano-Materials Company Engineers Tetrapod Quantum Dots to Improve Diagnostic Accuracy of Biomedical Assays and Devices


201306047919620SAN MARCOS, Texas, Nov. 7, 2013 /PRNewswire/ — Quantum Materials Corp. announced today that it has provided Tetrapod Quantum Dots (TQD) to an advanced medical device manufacturer to optimize performance of an “engineered spectrum” quantum dot-enabled light source to better provide useful data to researchers and practitioners that has not been easily discernible until now.

David Doderer, Vice President of R&D, explained, “We are fulfilling specific requests for  tetrapod quantum dots, in this case,  to create tailored light for investigation of tissue.  Differences between healthy and suspect tissue often can be better identified if the available fluorophores’ color combination is engineered for either true representation of color, or emphasized in the visible spectrum depending on the tissue type. I think our bespoke tetrapod quantum dots provide the depth of data necessary to highlight subtle differences that researchers and healthcare professionals need to efficiently understand disease and devise effective treatments.”

To achieve efficient healthcare in an increasingly demanding marketplace, the ability to get actionable information is crucial. Medical diagnostic assays currently count in the multi-millions per year and per country, and differences in tissues types at the cellular level are critically important for accuracy in results.  Conventional organic dyes and other types of fluorophores are currently used for luminescence in assays by researchers, but they have limitations sometimes preventing clear distinctions in reading the data. Broad data sets can tend to obscure patterns that might become clear by removing these uncertainties.

Tetrapod quantum dots address this issue well for biochemical detection and biomedical device application by providing a broad array of colors, which translates to increased number of pieces in the data set, and also precise tune-ability and stability for high contrast and distinctive identification certainty.  For biochemical detection, most typically in a rapid assay that provides a breadth of data in a single test kit, Quantum Materials has begun conversations with biotech researchers and companies needing narrow color emissions to provide clear identification when identifying particular targets by attaching to the desired organism or cell type when specifically functionalized.

As part of this effort, the Company is developing a suitable TQD film for medical devices while maintaining consistency in both uniformity and scalability. The Company believes this technology, one of several under review, could also successfully translate into Tetrapod Quantum Dot film applications such as general light applications, electronic displays and quantum dot solar cells.

 

 

 

 

Quantum Materials Corp. manufactures Tetrapod Quantum Dots for use in medical, display, solar energy and lighting applications through patent pending continuous-flow production process.  Quantum dot semiconductors enable a new level of engineered performance in a wide array of established consumer and industrial products. QMC’s volume manufacturing methods enable consistent QD quality and scalable cost reductions to drive innovative discovery to commercial success.

Safe Harbor statement under the Private Securities Litigation Reform Act of 1995

This press release contains forward-looking statements that involve risks and uncertainties concerning business, products, and financial results. Actual results may differ materially from the results predicted. More information about potential risk factors that could affect our business, products, and financial results are included in our annual report and in reports subsequently filed with the Securities and Exchange Commission (“SEC”). All documents are available through the SEC’s EDGAR System at http://www.sec.gov/ or www.QMCdots.com. We hereby disclaim any obligation to publicly update the information provided above, including forward-looking statements, to reflect subsequent events or circumstances.

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Tetrapod Nanocrystals as Fluorescent Stress Probes of Electrospun Nanocomposites


Abstract Image

 

201306047919620

A nanoscale, visible-light, self-sensing stress probe would be highly desirable in a variety of biological, imaging, and materials engineering applications, especially a device that does not alter the mechanical properties of the material it seeks to probe. Here we present the CdSe–CdS tetrapod quantum dot, incorporated into polymer matrices via electrospinning, as an in situ luminescent stress probe for the mechanical properties of polymer fibers. The mechanooptical sensing performance is enhanced with increasing nanocrystal concentration while causing minimal change in the mechanical properties even up to 20 wt % incorporation. The tetrapod nanoprobe is elastic and recoverable and undergoes no permanent change in sensing ability even upon many cycles of loading to failure. Direct comparisons to side-by-side traditional mechanical tests further validate the tetrapod as a luminescent stress probe. The tetrapod fluorescence stress–strain curve shape matches well with uniaxial stress–strain curves measured mechanically at all filler concentrations reported.

QMC & DOE collaborate on tetrapod quantum dot research


Mar 28, 2013    

QDOTS imagesCAKXSY1K 8Quantum Materials Corporation has recently developed and delivered customized tetrapod QD samples for applications being developed by the US Department of Energy National Lab researchers.

As one of the largest sponsors of U.S. technical and military research, the DOE helps to move innovative technologies into the commercial marketplace, creating new jobs and future industries.

Quantum Materials Corporation (QMC) has also agreed to supply customized tetrapod quantum dots to a U.S. government defense related agency in support of a nano-biological project.

More than 110 science-related Nobel Prizes have been awarded to DOE-associated researchers.

Department of Energy National (DOE) Labs, Energy Innovation Hubs and Technology Centers are developing quantum dot and other nanoscale applications.

Relevant applications include solar photovoltaics, batteries, biofuels, physics and biological sciences.

One institute working on the project is Los Alamos National Lab (LANL), which is exploring quantum dot-fluorescent proteins (QD-FP) in devices. They use pH-sensitive fluorescent protein acceptors to produce long-lived sensors for biological imaging. LANL’s use of quantum dots for precise cellular imaging produces valuable data for the hopeful cure or treatment of many diseases and conditions.

QMC believes its technology meets three NNI National Signature Initiatives objectives. These are new advanced materials (tetrapod quantum dots), mass production (continuous flow process) and nano-manufacturing (roll-to-roll printing).

Stephen Squires, QMC CEO commented, “The many DOE National Labs are in the forefront of quantum dot research and we welcome the opportunity to collaborate with them. QMC has enabling technologies to help fulfill NNI National Signature Initiatives years ahead of forecasts, advancing the nation’s research rapidly while perhaps saving the U.S. Government millions that can be redirected to application development.”

QMC currently offers high-brightness cadmium-based and ecological cadmium-free non-heavy metal tetrapod QD and can synthesize many Group II-VI inorganic mono or hybrid tetrapod quantum dots.

The firm intends to build out its quantum dot production facilities in the U.S. with full commercial production expected in the fourth quarter of 2013.

 

QDOTS imagesCAKXSY1K 8

Photoluminescent SiC tetrapods


qdot-imagescaf658qe-4.jpgAndrew P. Magyar, Igor Aharonovich, Mor Baram, Evelyn L. Hu

(Submitted on 29 Nov 2012)

Photoluminescent SiC tetrapods

Abstract: Recently, significant research efforts have been made to develop complex nanostructures to provide more sophisticated control over the optical and electronic properties of nanomaterials. However, there are only a handful of semiconductors which allow control over their geometry via simple chemical processes. Here, we present a molecularly seeded synthesis of a complex nanostructure, SiC tetrapods, and report on their structural and optical properties. The SiC tetrapods exhibit narrow linewidth photoluminescence at wavelengths spanning the visible to near infrared spectral range. Synthesized from low-toxicity, earth abundant elements, these tetrapods are a compelling replacement for technologically important quantum optical materials that frequently require toxic metals such as Cd and Se. This new, previously unknown geometry of SiC nanostructures is a compelling platform for biolabeling, sensing, spintronics and optoelectronics.

Comments: 14 pages, 4 figures
Subjects: Materials Science (cond-mat.mtrl-sci)
Cite as: arXiv:1211.6801 [cond-mat.mtrl-sci]
(or arXiv:1211.6801v1 [cond-mat.mtrl-sci] for this version)

Submission history

From: Andrew Magyar [view email] [v1] Thu, 29 Nov 2012 02:50:49 GMT  (1877kb,D)