Nano-Materials Company Engineers Tetrapod Quantum Dots to Improve Diagnostic Accuracy of Biomedical Assays and Devices


201306047919620SAN MARCOS, Texas, Nov. 7, 2013 /PRNewswire/ — Quantum Materials Corp. announced today that it has provided Tetrapod Quantum Dots (TQD) to an advanced medical device manufacturer to optimize performance of an “engineered spectrum” quantum dot-enabled light source to better provide useful data to researchers and practitioners that has not been easily discernible until now.

David Doderer, Vice President of R&D, explained, “We are fulfilling specific requests for  tetrapod quantum dots, in this case,  to create tailored light for investigation of tissue.  Differences between healthy and suspect tissue often can be better identified if the available fluorophores’ color combination is engineered for either true representation of color, or emphasized in the visible spectrum depending on the tissue type. I think our bespoke tetrapod quantum dots provide the depth of data necessary to highlight subtle differences that researchers and healthcare professionals need to efficiently understand disease and devise effective treatments.”

To achieve efficient healthcare in an increasingly demanding marketplace, the ability to get actionable information is crucial. Medical diagnostic assays currently count in the multi-millions per year and per country, and differences in tissues types at the cellular level are critically important for accuracy in results.  Conventional organic dyes and other types of fluorophores are currently used for luminescence in assays by researchers, but they have limitations sometimes preventing clear distinctions in reading the data. Broad data sets can tend to obscure patterns that might become clear by removing these uncertainties.

Tetrapod quantum dots address this issue well for biochemical detection and biomedical device application by providing a broad array of colors, which translates to increased number of pieces in the data set, and also precise tune-ability and stability for high contrast and distinctive identification certainty.  For biochemical detection, most typically in a rapid assay that provides a breadth of data in a single test kit, Quantum Materials has begun conversations with biotech researchers and companies needing narrow color emissions to provide clear identification when identifying particular targets by attaching to the desired organism or cell type when specifically functionalized.

As part of this effort, the Company is developing a suitable TQD film for medical devices while maintaining consistency in both uniformity and scalability. The Company believes this technology, one of several under review, could also successfully translate into Tetrapod Quantum Dot film applications such as general light applications, electronic displays and quantum dot solar cells.

 

 

 

 

Quantum Materials Corp. manufactures Tetrapod Quantum Dots for use in medical, display, solar energy and lighting applications through patent pending continuous-flow production process.  Quantum dot semiconductors enable a new level of engineered performance in a wide array of established consumer and industrial products. QMC’s volume manufacturing methods enable consistent QD quality and scalable cost reductions to drive innovative discovery to commercial success.

Safe Harbor statement under the Private Securities Litigation Reform Act of 1995

This press release contains forward-looking statements that involve risks and uncertainties concerning business, products, and financial results. Actual results may differ materially from the results predicted. More information about potential risk factors that could affect our business, products, and financial results are included in our annual report and in reports subsequently filed with the Securities and Exchange Commission (“SEC”). All documents are available through the SEC’s EDGAR System at http://www.sec.gov/ or www.QMCdots.com. We hereby disclaim any obligation to publicly update the information provided above, including forward-looking statements, to reflect subsequent events or circumstances.

Flotek Industries Announces Texas A&M Research Initiative on Nanotechnology and Unconventional Hydrocarbon Production


QDOTS imagesCAKXSY1K 8HOUSTON, July 29, 2013 /PRNewswire/ — Flotek Industries, Inc. announced today sponsorship of applied research at Texas A&M University to investigate the impact of nanotechnology on oil and natural gas production in emerging, unconventional resource plays.

“With the acceleration of activity in oil and gas producing shales, a better understanding of the impact of various completion chemistries on tight formations with low porosity and permeability will be key to developing optimal completion techniques in the future,” said John Chisholm, Flotek’s Chairman, President and Chief Executive Officer. “While we know Flotek’s Complex nano-Fluid chemistries have been successful in enhancing production in tight resource formations, we believe a more complete understanding of the interaction between our chemistries and geologic formations as well as a more precise comprehension of the physical properties and impact of our nanofluids in the completion process will significantly enhance the efficacy of the unconventional hydrocarbon completion process. This research continues our relationship with Texas A&M where we also are conducting research into acidizing applications in Enhanced Oil Recovery.”

Specifically, the research will focus its investigation on the oil recovery potential of complex nanofluids and select surfactants under subsurface pressure and temperature conditions of liquids-rich shales.

Dr. I. Yucel Akkutlu, Associate Professor of Petroleum Engineering in the Harold Vance Department of Petroleum Engineering at Texas A&M University will serve as the principal investigator for the project. Dr. Akkutlu received his Masters and PhD in Petroleum Engineering from the University of Southern California. He has over a decade of postgraduate theoretical and experimental research experience in unconventional oil and gas recovery, enhanced oil recovery and reactive flow and transport in heterogeneous porous media. He has recently participated in industry-sponsored research on resource shales including analysis of microscopic data to better understand fluid storage and transport properties of organic-rich shales.

“As unconventional resource opportunities continue to grow in importance to hydrocarbon production, understanding ways to maximize recovery will be key to improving the efficacy of these projects,” said Dr. Akkutlu. “The key to enhancing recovery will be to best understand robust, new technologies and their impact on the completion process. Research into complex nanofluid chemistries to understand the physical properties and formation interactions will play an integral role in the future of completion design to optimize recovery from unconventional hydrocarbon resources.”

The research will commence immediately. Inquiries regarding the research should be directed to Flotek.

About Flotek Industries, Inc.

Flotek is a global developer and distributor of a portfolio of innovative oilfield technologies, including specialty chemicals and down-hole drilling and production equipment. It serves major and independent companies in the domestic and international oilfield service industry. Flotek Industries, Inc. is a publicly traded company headquartered in Houston, Texas, and its common shares are traded on the New York Stock Exchange under the ticker symbol “FTK.”

For additional information, please visit Flotek’s web site at www.flotekind.com.

 

SOURCE  Flotek Industries, Inc.

Frost & Sullivan Acknowledges that PKC’s Biosensors: New Industry Standard in Pathogen Testing


QDOTS imagesCAKXSY1K 8MOUNTAIN VIEW, Calif., Feb. 13, 2013 /PRNewswire/ — Based on its recent analysis of the global biosensors market, Frost & Sullivan recognizes Pharmaco-Kinesis Corporation (PKC) with the 2013 Global Frost & Sullivan Award for New Product Innovation. The company has set a new standard in the biosensors market with its innovative, highly sensitive biosensor. This unique, multi-pathogen detection device utilizes electrochemical impedance spectroscopy (EIS) to detect pathogens such as E. coli 0157:H7 and the severe acute respiratory syndrome (SARS) virus. It offers higher sensitivity, accuracy, cost-savings. Other key advantages are its greater portability and reusability; and a shorter, less complex testing process than other biosensors in the market. This exhibits PKC’s market expertise and technological excellence.

PKC biosensors’ sample preparation is conducted in a controlled environment, which eliminates the possibility of contamination. Additionally, PKC biosensors require minimal human intervention and provide immediate, real-time pathogen detection. The product has a longer lifespan than similar solutions and can operate efficiently for more than five years with repeated use.

Unlike other pathogen test instruments that utilize test strips or incubators, PKC biosensors use a biosensor container with an electrochemical sensor attached to the base, along with a liquid mixer and a microprocessor that records biosensor readings. This entire device is encased in protective housing, which includes a container holder. This technology lets the pathogen detection status be obtained remotely in real time using radio frequency identification (RFID) readers.

“PKC’s new biosensor offers a number of advantages over the other pathogen test solutions in the market. For example, the lateral flow method requires about eight hours for sample preparation and testing, while PKC’s new technology takes only four hours,” said Frost & Sullivan Research Analyst Dr. Rajender Thusu . “Further, PKC’s technology can detect E. coli 0157:H7, even when it is present in colonies of hundreds, a considerably smaller population than required by other test methods.”

Additionally, PKC’s technology requires a consumable input of only bacteria culture medium, which makes this solution highly cost-effective. Using a vertical orientation of colonies, instead of existing test solutions’ horizontal orientation, significantly accelerates the detection process.

As PKC’s biosensors also offer automated signal generation and high ease of use, it does away with the need to train technicians or use expensive additional equipment. The PKC test instrument requires only an initial investment, instead of the recurring investments needed by other test solutions. Overall, PKC lowers the cost of pathogen testing to almost half of that of lateral-flow technology.

“Although designed for use across a number of application areas, PKC’s biosensors are used primarily in food processing,” noted Dr. Thusu. “They also demonstrate high growth potential in the application areas of patient care monitoring, biodefense, environmental monitoring, and infection control. Another key application area detection of biomarkers related to all cancer types, genetic makers, DAN, RNA and CNS battery of diseases including Alzheimer’s biomarkers, Parkinson and MS.”

PKC’s constant focus on tracking emerging customer needs enables it to introduce industry-first products and solutions designed to offer high customer value and increased return on investment (ROI). PKC is also developing biosensors using nanotechnology, including nanobiosensors, for both in-vivo and in-vitro monitoring of biomarker levels.

PKC is currently working on the first-generation nano-impedance biosensor (NIB) that exhibits the capability to detect high proteins like vascular endorphin growth factor (VEGF). This is likely to enable real-time analysis of tumors in the human body without the need for a blood draw or magnetic resonance imaging (MRI) test.  Every twenty four hours, the body of each human on our planet produces one million cancer cells. Our immune system fights these cancer cells and most often wins the battle every day. Due to weakness of the immune system and reasons that are still unknown, one cancer cell from these one million cells can remain in the body. This rogue cancer cell will then start to grow and can metastasize. The science and medical community unequivocally agrees that – were we capable of detecting these metastatic cancer cells before they grow to about 1 gram in critical mass (about 1 cc in volume) – current treatment modalities could defend against the cancer and save every life. PKC VEGF NIB will give cancer patients to hopefully never experience the pain and suffering of experiencing chemotherapy, tumor resection and death.  The first PKC commercial version of NIB for VEGF will be ready in about six months.

Each year, Frost & Sullivan presents this award to the company that has developed an innovative element in a product by leveraging leading-edge technologies. The award recognizes the value-added features/benefits of the product and the increased ROI it offers customers, which, in turn, increases customer acquisition and overall market penetration potential.

Frost & Sullivan Best Practices Awards recognize companies in a variety of regional and global markets for demonstrating outstanding achievement and superior performance in areas such as leadership, technological innovation, customer service and strategic product development. Industry analysts compare market participants and measure performance through in-depth interviews, analysis and extensive secondary research to identify best practices in the industry.

About Pharmaco-Kinesis Corporation (PKC)

PKC is an advanced medical device company at pre-commercialization stage that aims to optimize the healing of the human body through proprietary local Smart Drug Delivery Systems™ and associated devices to measure biological responses.

This news release contains “forward-looking statements” within the meaning of the safe harbor provisions of the United States Private Securities Litigation Reform Act of 1995. Such statements are based upon the current beliefs and expectations of the management of Pharmaco-Kinesis Corporation and are subject to significant risks and uncertainties. Actual results may differ materially from those set forth in the forward-looking statements. The company undertakes no obligation to publicly update any forward-looking statement, whether as a result of new information, future events or otherwise.

PR Newswire (http://s.tt/1zK8s)

Quantum Materials Corporation Receives Prestigious Frost and Sullivan Award


QDOTS imagesCAKXSY1K 8Quantum Materials Corp Receives 2012 North American Enabling Technology Award For Advanced Quantum Dot Manufacturing From Frost & Sullivan.

 

 

CARSON CITY, Nev., Dec. 18, 2012 /PRNewswire/ — Quantum Materials Corporation (QMC), the first manufacturer of Tetrapod Quantum Dots by a mass production continuous flow chemistry process, has been honored with Frost & Sullivan’s 2012 North American Enabling Technology Award for Advanced Quantum Dot Manufacturing. QMC’s “enabling technology” overcomes all quantum dot industry problems by delivering high-quality, lower-cost, and uniform quantum dots in commercial quantities for the reliable supply necessary for industrial production commitments. 

Frost & Sullivan rated QMC higher than competitors in all criteria, specifically highlighting QMC’s low cost of manufacture, mass-production capability, potential for market acceptance, and variety of hybrid quantum dots before concluding, “QMC’s QD technology is poised for large-scale adoption in diverse fields, such as lighting, displays, solar energy, sensors, optoelectronics, and flexible electronics.”

Frost & Sullivan Senior Research Analyst Shyam Krishnan said, “There is no question that the future is very bright for quantum dots. Their ability to interact with photons, electrons, and chemicals to make useful energy, light or other nanoscale actions is as yet unmatched among nanoparticles. Quantum Materials Corporation’s patented quantum dot synthesis that allows scalable mass production will allow them to service a multitude of industries in the near future. That is the reason they have earned the Frost & Sullivan 2012 North America Enabling Technology Award for Advanced Quantum Dot Manufacture.”

Frost & Sullivan is in its 50th year in business with a global research organization of 1,800 analysts and consultants who monitor more than 300 industries and 250,000 companies. The company’s research philosophy originates with the CEO’s 360-Degree Perspective™, which serves as the foundation of its TEAM Research™ methodology. This unique approach enables us to determine how best-in-class companies worldwide manage growth, innovation and leadership.

The total market for quantum dots is expected to reach $7.48 billion by 2022, at a CAGR of 55.2 percent from 2012 to 2022 according to the market research report, “Quantum Dots Market – Global Forecast & Analysis (2012–2022)” by MarketsandMarkets.

“QMC is grateful for this exceptional recognition by Frost & Sullivan of our technologies, innovative manufacturing abilities, and focus to bring quantum dot commercialization forward in partnership with other advanced technology companies,” stated Stephen B. Squires, Quantum Materials Corp CEO and founder. “We are developing solid working relationships with like-minded companies, exploring this new ability to go from drawing board into production years before any recent forecast has predicted it would be possible.”

quantum material corp logoQUANTUM MATERIALS CORPORATION has a steadfast vision that advanced technology is the solution to global issues related to cost, efficiency and increasing energy usage. Quantum dot semiconductors enable a new level of performance in a wide array of established consumer and industrial products, including low-cost flexible solar cells, low-power lighting and displays, and biomedical research applications. Quantum Materials Corporation intends to invigorate these markets through cost reduction and moving laboratory discovery to commercialization with volume manufacturing methods to establish a growing line of innovative, high-performance products

 

Anti-counterfeiting with DNA nanotechnology


Animation of the structure of a section of DNA...

Animation of the structure of a section of DNA. The bases lie horizontally between the two spiraling strands. (Photo credit: Wikipedia)

Note To Readers: This is truly an a-m-a-z-i-n-g technology! The benefits provided by this technology go beyond ‘counterfeiting’ applications. As always, your comments and feedback are encouraged and welcomed!  Cheers!  – BWH –

Posted: November 6, 2012

Anti-counterfeiting with DNA nanotechnology(Nanowerk Application Note) A study by the OECD (pdf) concluded that international trade in counterfeit and pirated goods could have accounted for up to USD 250 billion in 2007. The OECD estimates that the share of counterfeit and pirated goods in world trade is close to 2%. And these figures do not even include domestically produced and consumed products, or non-tangible pirated digital products. Industry segments for which counterfeits are a significant problem include pharmaceuticals, airplane parts, auto parts, and designer clothing.Recent developments in nanotechnology have enabled significant improvement in the field of anti-counterfeiting measures.

One company for instance is working on fluorescent nanostructures to improve banknote security; another one has developed DNA tags for deposition on nanoelectronics wafers and computer chips to ensure the integrity and security of processed wafers.DNA-based protection technologies are especially suitable for anti-counterfeiting measures. Genuine-ID, a Swiss start-up company, has developed state-of-the-art security products based on DNA code which they call the Genuine-ID product passport.Here is how it works:The DNA molecules are added a products raw material during the production process. Only 1 ppm (one part per million) is required to uniquely mark the material. That is one gram per one ton of raw material.adding DNA security codeImage: Genuine-IDThe DNA

 

Therefore there material properties remain unchanged. No extra production steps are required. No extra molecules are encapsulated in a silicon dioxide microparticle in order to protect them from the harsh conditions during production and the product life cycle. These microparticles are nothing other than very small glass balls with a diameter of about 100 nm.The DNA molecular structure can be read as a mathematical code based on the four DNA molecules – Adenine (A), Cytosine (C), Guanine (G), and Thymine (T). So a DNA code, in contrast to the binary code used in IT security, is a combination of the letters A, C, G and T. A 10-digit code could look like this: C-G-A-C-T-T-G-A-C-A.

In the case of the Genuine-ID product passport, a 64-digit code-length is used. The number of possible combinations is therefore 4x4x4….x4 and that 64 times. Mathematically that is written as: 464 = 3.4E38. That is 34 followed by 37 zeroes.A copy of every unique DNA code that is added to a product – the so called DNA primer – is kept as a sample in a safe deposit at a Swiss bank. For security reasons, no electronic version of the DNA-sequence is stored. In the case of a sample test inquiry, a very small probe (1 mg) is taken from the product and paired with the original DNA primer for a PCR (polymerase chain reaction) test. Only when the DNA code from the two samples are a perfect match will the test result be positive.The analysis lasts about 2 hours. Many probes can be analyzed simultaneously.

The PCR analysis is a proven and established DNA analysis method which is used for blood tests (HIV-test, etc.) and paternity tests. The result is unique and 100% certain.Depending on the application, there are three variations of DNA coding available from Genuine-ID:Genuine-ID Seal:

Labels or seals, starting from very low quantities, include unique and traceable Genuine-ID coding. This is the quick and easy way to stamp a product with the unique Genuine-ID product passport. The label can be added to any product (stitched or glued on textiles) as guarantee of authenticity and quality.

Genuine-ID polymers: Additive for thermoplastic processing. Genuine-ID is ready compounded in thermoplastic polymers (PCC; LD-PE). No additional processing steps are needed. Genuine-ID polymers is the ultimate application of the Genuine-ID material passport. The material itself is uniquely marked. No barcodes holograms, labels or other add-on’s are needed. The code is stored everywhere in the material.The Genuine-ID polymer is mixed into the material as a standard additive. Very low quantities are needed. Only 0.1 ppm (100 milligram per ton) of particles are required to mark the material sufficiently.

Genuine-ID particles: Any liquid or cream can be marked with Genuine-ID particles. Genuine-ID particles can be mixed into liquids, gels, creams and other fluids by the customer. The particles are completely invisible and do not change the properties or functionality of the liquid. Only tiny amounts of particles are required for identification (0.1 – 1 ppm). The base material of Genuine-ID particles (SiO2) is approved as food additive E551 (up to 10 grams per kilo) and is used as a thickener in the food industry. The silica is not resorbed by the organism and egested unchanged.By Michael Berger. Copyright © Nanowerk

Read more: http://www.nanowerk.com/spotlight/spotid=27226.php#ixzz2CVYlntE1