A Declaration of War- The CCP and A Personal Statement Regarding COVID 19 – What ‘We’ Can Do Now


A Declaration of War – A Personal Statement on COVID 19

CBS News ServiceThe number of deaths caused by the coronavirus worldwide reached at least 13,049, including 340 in the U.S. and 4,825 in Italy, where the devastating virus has brought the country to its knees.

New York TimesItaly hit a grim milestone Saturday by recording record-breaking death tolls two days in a row. The country announced its biggest day-to-day increase of infections, which rose to 53,000 people, with nearly 800 new deaths. As bodies pile up in Italian hospitals, morgues and churches, and as medical workers plead for more help, there is no sign yet that Italy is taming its arc of its contagion.

New York Governor Andrew Cuomo said 114 people had died in the state, and said hospital capacity needs to double to meet the anticipated need for beds to treat patients.

And in More News …

LIVE: Johns Hopkins University – ArcGIS Online for Johns Hopkins

Fox News … Who was Li Wenliang, the Chinese doctor who warned about the coronavirus?

Fox News … Coronavirus and China – Here’s what Americans should consider

Axios … Timeline: The early days of China’s coronavirus outbreak and cover-up

TOPSHOT-CHINA-HEALTH-VIRUS

COVID 19: 22 March, 2020

I just heard what I think makes a tremendous amount of GOOD SENSE. (In my Opinion)

In as much as the CCP (Chinese Communist Party) HAS DECLARED WAR on the US and the World, either by INTENTION or by OMISSION … WE SHOULD CONSIDER OURSELVES NOW AT WAR, and we need to ACT ACCORDINGLY.

My Post is neither RACIST nor meant to incite PANIC. I am URGING HOWEVER THAT “WE ALL ACT TOGETHER – just as …  in the time of War.!”

To Quote General S. Patton – “A good plan, violently executed now, is better than a perfect plan next week” — George Patton.

FIRST: We need to act just as thE U.S. did after the attack on Pearl Harbor December 7, 1947. “A Day that will (has) lived in infamy.” Everyone put it into High Gear! We need to respond FINANCIALLY, ECONOMICALLY, INDUSTRIALLY and HEALTH CARE SYSTEM “WISE.” We need to ACT NOW!

SECOND: WE NEED TO MOBILIZE ALL OF INDUSTRY to first supply the needs of the Medical / Health Care sectors (The War). WE NEED TO HIT THIS VIRUS HARD NOW! QUARANTINES. EMERGENCY MEASURES (Maybe areas of Martial Law?), Border Closures, SUPPLY CHAINS (Food, Medical, Industrial. Logistics and Transportation).

All  of this in an effort to (1) Hit the Pandemic hard and quickly, limit Community Transmission and SHORTEN THE DURATION and RATE of DEATH from COVID19.

And (2) We need to bring our Critical Manufacturing and Supply Chains home … back to a Country and Countries that are trusted, are transparent and forthcoming.

Can we even imagine what 10? 20? 30? days would have meant to those suffering in Italy, New York and around the globe today? How many lives may have been saved if only the CCP (Communist Chinese Party) had acted sooner?

What if the CCP  had acted and not suppressed news reports before/ during the time when Hundreds of Thousands of unsuspecting Chinese gathered during Chinese New Year with Friends and Family and then returned “home”?  (Current COVID19 Count over 225,000 infected; over 8,800 Dead in China alone, 13,000 and climbing Worldwide)

How many flights could have been diverted? How many self-directed quarantines could have made the difference?  Dare we say that those who have lost close friends and loved ones due to CCP’s lack of honesty and forthright action have a case for Criminal Negligence? **

Again, Quoting a perhaps forgot but very successful and War Winning General from WWII – “A good plan, violently executed now, is better than a perfect plan next week” — George S. Patton

“TIME – IS OF THE ESSENCE” to save LIVES!

Coronavirus, virus which causes SARS and MERS

THIRD: WE NEED TO GET CASH INTO THE HANDS OF MAIN STREET, SMALL BUSINESSES, THE LITTLE GUY to bridge the gap, so that as we shut down the U.S  (and other Countries)  via QUARANTINE to (1) STOP the spread, to provide (2) TIME for our Health Care and Medical Communities to (3) Respond and Ramp up …….  so that WE ALL WILL SURVIVE, Financially, Economically and Health Wise.

Corona 2 DD-COMPOSITE-CORONAVIRUS-GRAPHIC-2

FOURTH: TO SURVIVE AND RETURN TO OUR ROBUST FINANCIAL AND ECONOMIC STATUS (Worldwide) PRIOR TO THE CHINESE OUTBREAK and the DECLARATION OF WAR, OUR FEDERAL GOVERNMENT (US Treasury and The Fed) NEED TO PROVIDE MASSIVE LIQUIDITY  (Merge the Treasury and Fed Bank Balance Sheets) TO THE SYSTEM BOTH NOW AND POST COVID 19.

DO IT!! DO IT NOW!!!

What ‘We’ Can Do

•  SELF-QUARANTINE! STAY HOME! DO NOT GO OUT UNLESS NECESSARY (Food, Medical) Rule: At least 6 Feet apart in Public Places. ONLY Groups smaller than 10. YES THIS ALSO INCLUDES YOU YOUNG PEOPLE!  You make think you are “bullet-proof” YOU ARE NOT!

Wash/Clean Your Hands, Face, Clothes and Surfaces

Check on and Look-In on those MOST VULNERABLE in our “At Risk Population”

Cover Cough and Sneezes. BE CONSIDERATE!

Random-Acts-of-Kindness 1-Logo

And most IMPORTANT …

Please be Kind to One Another … DO WHAT YOU CAN, WHERE YOU CAN, HOW YOU CAN. PRACTICE RANDOM ACTS OF KINDNESS!! 😀😀😀❤️❤️❤️

PLEASE SHARE FREELY AND AS YOU DEEM APPROPRIATE.

 – GOD BLESS

** In late December in the COVID19 Timeline, Chinese Officials were still maintaining the COVID 19 (as it would come to be known) was “not being transmitted from Human to Human.”

Johns Hopkins University ~ More flexible Nanomaterials can make Fuel Cell Cars Cheaper


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A new method of increasing the reactivity of ultrathin nanosheets, just a few atoms thick, can someday make fuel cells for hydrogen cars cheaper, finds a new Johns Hopkins study.

Johns Hopkins U goldilocksthA platinum-like metal only five atomic layers thick is “just right” for optimizing the performance of a fuel cell electrode. Credit: Johns Hopkins University image/Lei Wang

 

A report of the findings, to be published Feb. 22 in Science, offers promise towards faster, cheaper production of electrical power using fuel cells, but also of bulk chemicals and materials such as hydrogen.

“Every material experiences surface strain due to the breakdown of the material’s crystal symmetry at the . We discovered a way to make these crystals ultrathin, thereby decreasing the distance between atoms and increasing the material’s reactivity,” says Chao Wang, an assistant professor of chemical and biomolecular engineering at The Johns Hopkins University, and one of the study’s corresponding authors.

Strain is, in short, the deformation of any material. For example, when a piece of paper is bent, it is effectively disrupted at the smallest, atomic level; the intricate lattices that hold the paper together are forever changed.

In this study, Wang and colleagues manipulated the strain effect, or distance between atoms, causing the material to change dramatically. By making those lattices incredibly thin, roughly a million times thinner than a strand of human hair, the material becomes much easier to manipulate just like how one piece of paper is easier to bend than a thicker stack of paper.

“We’re essentially using force to tune the properties of thin metal sheets that make up electrocatalysts, which are part of the electrodes of fuel cells,” says Jeffrey Greeley, professor of chemical engineering at Purdue and another one of the paper’s corresponding authors. “The ultimate goal is to test this method on a variety of metals.”

“By tuning the ‘ thinness, we were able to create more strain, which changes the material’s properties, including how molecules are held together. This means you have more freedom to accelerate the reaction you want on the material’s surface,” explains Wang.

One example of how optimizing reactions can be useful in application is increasing the activity of catalysts used for fuel cell cars. While fuel cells represent a promising technology toward emission-free electrical vehicles, the challenge lies in the expense associated with the precious  such as platinum and palladium, limiting its viability to the vast majority of consumers. A more active catalyst for the fuel cells can reduce cost and clear the way for widespread adoption of green, renewable energy.

More flexible nanomaterials can make fuel cell cars cheaper
Chao Wang, a Johns Hopkins assistant professor of chemical and biomolecular engineering, in his lab with postdoctoral fellow Lei Wang, another author of the related research article. Credit: Will Kirk/Johns Hopkins University

Wang and colleagues estimate that their new method can increase catalyst activity by 10 to 20 times, using 90 percent less of precious metals than what is currently required to power a .

“We hope that our findings can someday aid in the production of cheaper, more efficient fuel cells to make environmentally-friendly cars more accessible for everybody,” says Wang.

 Explore further: Gilding technique inspired by ancient Egyptians may spark better fuel cells for tomorrow’s electric cars

More information: L. Wang el al., “Tunable intrinsic strain in two-dimensional transition metal electrocatalysts,” Science (2019). science.sciencemag.org/cgi/doi … 1126/science.aat8051

 

Nano-Fiber coating prevents infections of prosthetic joints: Johns Hopkins University


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A titanium implant (blue) without a nanofiber coating in the femur of a mouse. Bacteria are shown in red and responding immune cells in yellow. Credit: Lloyd Miller/Johns Hopkins Medicine

In a proof-of-concept study with mice, scientists at The Johns Hopkins University show that a novel coating they made with antibiotic-releasing nanofibers has the potential to better prevent at least some serious bacterial infections related to total joint replacement surgery.

A report on the study, published online the week of Oct. 24 in Proceedings of the National Academy of Sciences, was conducted on the rodents’ knee joints, but, the researchers say, the technology would have “broad applicability” in the use of orthopaedic prostheses, such as hip and knee total joint replacements, as well pacemakers, stents and other . In contrast to other coatings in development, the researchers report the new material can release multiple antibiotics in a strategically timed way for an optimal effect.

“We can potentially coat any metallic implant that we put into patients, from prosthetic joints, rods, screws and plates to pacemakers, implantable defibrillators and dental hardware,” says co-senior study author Lloyd S. Miller, M.D., Ph.D., an associate professor of dermatology and orthopaedic surgery at the Johns Hopkins University School of Medicine.

Surgeons and biomedical engineers have for years looked for better ways —including antibiotic coatings—to reduce the risk of infections that are a known complication of implanting artificial hip, knee and shoulder joints.

Every year in the U.S., an estimated 1 to 2 percent of the more than 1 million hip and knee replacement surgeries are followed by infections linked to the formation of biofilms—layers of bacteria that adhere to a surface, forming a dense, impenetrable matrix of proteins, sugars and DNA. Immediately after surgery, an acute infection causes swelling and redness that can often be treated with intravenous antibiotics. But in some people, low-grade chronic infections can last for months, causing bone loss that leads to implant loosening and ultimately failure of the new prosthesis. These infections are very difficult to treat and, in many cases of chronic infection, prostheses must be removed and patients placed on long courses of antibiotics before a new prosthesis can be implanted. The cost per patient often exceeds $100,000 to treat a biofilm-associated prosthesis infection, Miller says.

Major downsides to existing options for local antibiotic delivery, such as antibiotic-loaded cement, beads, spacers or powder, during the implantation of medical devices are that they can typically only deliver one antibiotic at a time and the release rate is not well-controlled. To develop a better approach that addresses those problems, Miller teamed up with Hai-Quan Mao, Ph.D., a professor of materials science and engineering at the Johns Hopkins University Whiting School of Engineering, and a member of the Institute for NanoBioTechnology, Whitaker Biomedical Engineering Institute and Translational Tissue Engineering Center.

Over three years, the team focused on designing a thin, biodegradable plastic coating that could release multiple antibiotics at desired rates. This coating is composed of a nanofiber mesh embedded in a thin film; both components are made of polymers used for degradable sutures.

To test the technology’s ability to prevent infection, the researchers loaded the nanofiber coating with the antibiotic rifampin in combination with one of three other antibiotics: vancomycin, daptomycin or linezolid. “Rifampin has excellent anti-biofilm activity but cannot be used alone because bacteria would rapidly develop resistance,” says Miller. The coatings released vancomycin, daptomycin or linezolid for seven to 14 days and rifampin over three to five days. “We were able to deploy two antibiotics against potential infection while ensuring rifampin was never present as a single agent,” Miller says.

The team then used each combination to coat titanium Kirschner wires—a type of pin used in orthopaedic surgery to fix bone in place after wrist fractures—inserted them into the of anesthetized mice and introduced a strain of Staphylococcus aureus, a bacterium that commonly causes biofilm-associated infections in orthopaedic surgeries. The bacteria were engineered to give off light, allowing the researchers to noninvasively track infection over time.

Miller says that after 14 days of infection in mice that received an antibiotic-free coating on the pins, all of the mice had abundant bacteria in the infected tissue around the knee joint, and 80 percent had bacteria on the surface of the implant. In contrast, after the same time period in mice that received pins with either linezolid-rifampin or daptomycin-rifampin coating, none of the mice had detectable bacteria either on the implants or in the surrounding tissue.

“We were able to completely eradicate infection with this coating,” says Miller. “Most other approaches only decrease the number of bacteria but don’t generally or reliably prevent infections.”

After the two-week test, each of the rodents’ joints and adjacent bones were removed for further study. Miller and Mao found that not only had infection been prevented, but the bone loss often seen near infected joints—which creates the prosthetic loosening in patients—had also been completely avoided in animals that received pins with the antibiotic-loaded coating.

Miller emphasized that further research is needed to test the efficacy and safety of the coating in humans, and in sorting out which patients would best benefit from the coating—people with a previous prosthesis joint infection receiving a new replacement joint, for example.

The polymers they used to generate the nanofiber coating have already been used in many approved devices by the U.S. Food and Drug Administration, such as degradable sutures, bone plates and drug delivery systems.

Explore further: Early studies show microspheres may prevent bone infections after joint replacement

More information: Polymeric nanofiber coating with tunable combinatorial antibiotic delivery prevents biofilm-associated infection in vivo, Proceedings of the National Academy of Sciences, www.pnas.org/cgi/doi/10.1073/pnas.1613722113