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“Great Things from Small Things” – The Next Industrial Revolution!

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“Nanotechnology – Great Things from Small Things”


About Genesis Nanotechnology, Inc.

Genesis Nanotechnology, Inc. (GNT) is an Applied Nanotechnology IP Holding and Development Company. GNT acquires, holds and develops Patents & Trade Secrets & Processes, then markets those IP’s for Nanomaterials across a broad spectrum of mature Industry Markets. GNT creates ‘enterprise value’ & the opportunity for multiple revenue streams by obtaining the rights to & developing early stage ‘Nano-Intellectual Properties’ (NIP).

GNT is actively evaluating patented and emerging nanotechnology opportunities for Joint Venture and Strategic Alliances. GNT creates short and long term revenues, in addition to ‘enterprise value’ by:  Identifying, Developing, Integrating and then Commercializing, nanotechnologies that demonstrate significant new disruptive capabilities, enhance new or existing product performance and/or beneficially impact input cost reductions and efficiencies and therefore will achieve a sustainable and competitive advantage in their chosen market sector.

Market and Industry ApplicationsApplications-of-Nanomaterials-Chart-Picture1

 Applied Nanomaterials are being integrated into existing markets and are facilitating emerging products and technologies that are being developed by a very deep field of mature and financially capable companies: [Examples: Hitachi, Samsung, Siemens Lockheed Martin, 3M, DOW, NVC, Merck, Glaxo Smith-Kline]

Nano-Engineered Materials are impacting Medicine, Consumer Electronics, Energy Solutions and Advanced Fabrics. [Examples: Nano-Medicine, (Cancer Treatment Diagnostics, Drug Delivery & Therapy); Solid-State Lighting, Screen Displays (LED, LCD,QLED), Semi-Conductors, Security Inks, Paints, Coatings & Filters, QD Enabled Solar Cells, Ion-Lithium & Organic Batteries, Water Filtration & Desalinization, Military Armor and Identification and Natural Gas & Oil Market applications.]

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Thank You! Genesis Nanotechnology – “Great Things from Small Things”

Derek Paravicini and Adam Ockelford: In the key of genius

imagesCAMR5BLR Einstein Judging a FishPublished on Aug  9, 2013

GNT writes: In a departure from all things small … we are truly amazed by this story. From the ‘human capacity to overcome’ perspective to the ‘backstory’ of the a-m-a-z-I-n-g capabilities of the body human … please enjoy and appreciate this truly amazing talent!  


Born three and a half months prematurely, Derek Paravicini is blind and has severe autism. But with perfect pitch, innate talent and a lot of practice, he became an acclaimed concert pianist by the age of 10. Here, his longtime piano teacher, Adam Ockelford, explains his student’s unique relationship to music, while Paravicini shows how he has ripped up the “Chopsticks” rule book. (Filmed at TEDxWarwick.)



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Nano-Antioxidant With Longer Shelf Life For Better Anti-Aging Cremes and Food

QDOTS imagesCAKXSY1K 8Scientists from ETH Zurich have developed a nanomaterial  that protects other molecules from oxidation. Unlike many such active  substances in the past, the ETH-Zurich researchers’ antioxidant has a  long shelf life, which makes it just the ticket for industrial  applications.

There is a lot of talk about antioxidants. These chemical compounds are found in many fruit and vegetable varieties, coffee, tea and red wine, and are generally regarded as healthy. After all, antioxidants protect the body’s own proteins and the genetic substance from oxidation. Antioxidants are also used in industry, including as food additives to preserve items for longer or exploit the health aspect as a selling point. They are in food packaging or car tires to prevent the synthetic material or rubber from becoming brittle. And in the cosmetics industry creams with antioxidants are advertised as anti-aging products.

The problem in using antioxidants, however, is that many of these molecules are not actually very stable in themselves. For instance, they are oxidized in the presence oxygen and gradually lose their antioxidant effect. Researchers under Yiannis Deligiannakis, a visiting professor at the Institute of Process Engineering, have now developed a special nanoantioxidant that is considerably more stable than its conventional counterparts, which means it can be stored more easily and is effective in smaller amounts.

Nanoparticles prevent interaction

The ETH-Zurich scientists’ nanoantioxidant is composed of a silicon dioxide nanoparticle and the naturally occurring antioxidant gallic acid, whereby the two parts are firmly bonded. “Gallic acid is one of the molecules with the best antioxidant activity,” explains Georgios Sotiriou, who was involved in the project as a postdoc at the Institute of Process Engineering before moving to Harvard University. However, as with other antioxidants, gallic acid molecules soon lose their effect, especially since they like to latch onto other gallic acid molecules and thus deactivate each other. By combining them with the silicon dioxide, however, the researchers were able to suppress this process. After all, the large nanoparticles compared to the gallic acid molecules prevent the latter from interacting with each other: for reasons of space, they are no more capable of doing so than passengers in two hot-air balloons are of reaching out and touching each other.

ETH Zurich's researchers coupled gallic acid with silicon dioxide nanoparticles to stabilize the antioxidant.
(Photo : Edisa Balje / ETH Zurich) ETH Zurich’s researchers coupled gallic acid with silicon dioxide nanoparticles to stabilize the antioxidant.

“Our nanoantioxidant has the same outstanding effect as gallic acid, but can be sold as a product with a long shelf life for industry,” says Deligiannakis. Moreover, the nanoantioxidant is temperature-resistant and could thus protect food that is pasteurised or polymers that are produced at high temperatures. Conventional antioxidants become inactive at these temperatures.

A safe combination

The researchers have now patented their new product and are currently in talks with industrial partners with regard to licensing. The scientists do not expect any major hurdles as far as the safety of the molecule is concerned: both gallic acid and the silicon dioxide nanoparticles are deemed harmless, have been approved by the authorities – including for use in food – and are in active usage. The scientists thus expect tests to confirm that the combination molecule is also safe for cosmetics and food. — Source: Fabio Bergamin, ©2013 ETH Zurich (Federal Institute of Technology Switzerland), posted by Mark Hoffman 


Deligiannakis Y, Sotiriou GA, Pratsinis SE: Antioxidant and Antiradical SiO2 Nanoparticles Covalently Functionalized with Gallic Acid. ACS Applied Materials & Interfaces, 2012, 4, 6609-6617, doi: 10.1021/am301751s

$244 BILLION in Renewable Energy Investments: 2012

Jun 14, 2013

REN21 Frankfort School - UNEP reports renewable energy investments globally
Around $244 billion was invested in renewable energy in 2012, with a geographic shift toward developing countries, according to sister reports released by REN21, a global renewable energy policy network, and the Frankfurt School – UNEP Collaborating Centre for Climate & Sustainable Energy Finance.

According to the reports, 115 GW of new renewable capacity was installed globally in 2012, although global investments fell 12 percent from 2011. The drop in investment was mainly because of dramatically lower solar prices and weakened U.S. and European markets, according to the report from the Frankfurt School.

Despite that, 2012 remains the second highest year in history for renewable energy investments, with a continuing upward trend in developing companies. The reports note that investments in developing countries were around $112 billion, compared to $132 billion in developed countries.

The reports noted that renewable energy made up about half the total electric capacity addition in the U.S. in 2012, with more capacity added from wind power than any other technology. Total investment in renewable energy was down 34 percent to $36 billion, however. The reports cite uncertainties over U.S. policy as the main reason for the decrease in total renewable investment.

The largest investment in renewable energy was made in China, where a 22 percent increase raised the total investment in 2012 to $67 billion, largely due to a jump in solar investment, according to the reports.

Wind power accounted for about 39 percent of the renewable energy capacity added in 2012, followed by hydropower and solar photovoltaic power, which each accounted for about 26 percent of new capacity.

Renewable Energy: World Invests $244 billion in 2012, Geographic Shift to Developing Countries. Installed capacity continues to grow as solar prices drop 30-40%, new wind installations surge

For only the second time since 2006, global investments in renewable energy in 2012 failed to top the year before, falling 12% mainly due to dramatically lower solar prices and weakened US and EU markets.

There was a continuing upward trend in developing countries in 2012, with investments in the South topping $112 billion vs $132 billion in developed countries – a dramatic change from 2007, when developed economies invested 2.5 times more in renewables (excluding large hydro) than developing countries, a gap that has closed to just 18%.

The main issue holding back investment last year was instability in the policy regime for renewable energy in important developed-economy markets. Future investment is likely to coalesce in countries that can offer policies that command investor confidence, plus the need for extra generating capacity and strong renewable power resources.

After being neck-and-neck with the US in 2011, China was the dominant country in 2012 for investment in renewable energy, its commitments rising 22% to $67 billion, thanks to a jump in solar investment. But there were also sharp increases in investment for several other emerging economies, including South Africa, Morocco, Mexico, Chile and Kenya.

The other major theme of 2012 was a further, significant reduction in the costs of solar photovoltaic technology. The levelised cost of generating a MWh of electricity from PV was around one third lower last year than the 2011 average. This took small-scale residential PV power, in particular, much closer to competitiveness.

The Moneyball strategy is the future for venture capital firms?

QDOTS imagesCAKXSY1K 8*** Note To Readers: I know, I know … some of you will read this with a seasoned sense of skeptisim … but more often than not, with enough data points and with “financial analysis tools” the approach to picking ‘winners and losers’ when it comes to new business ventures … becomes less and less dependent upon ‘ye old spin the bottle’ approach! Enjoy … “Live Long and Prosper!”  BWH

January 10, 2013 4:44 PM
Matt  Oguz


“Money Ball”

Traditional venture capital invests with a “gut” feeling approach, and as  VentureBeat’s Christina Farr  recently  put it, “Relying on gut feeling simply isn’t good enough anymore”.

Investors suffer from a number of cognitive biases. The biggest, most  powerful and most dangerous bias in Silicon Valley today is called the “herd  mentality” or “bandwagon effect.” It’s difficult to oppose the general  consensus.

As investors, this and other cognitive biases skew our decision-making  process every day. How do you get around it? We believe that the answer lies in  mathematics. If we can work with models that are built to protect us from human  biases, guide us through the turbulent waters of high-risk investing and  incorporate factors of safety, that would be a better option than swinging for  the fences to make up for losses.

Most people in traditional VC, including  Blumberg Ventures’ Jon Soberg would make the claim that there’s very little  data to work with. In a recent post in VentureBeat, Soberg comes up with a  heuristic statistic to prove that “most investments fail.”

I would argue that historical data is available. When you actually take a  deeper look at the numbers, you’ll find some definitive patterns. The returns  actually resemble a log-normal or log-levy distribution, not a normal  distribution. We actually have a strong grasp of what the return data looks  like, and do not need to accept the widely-held belief that most startups  fail.

Screen shot 2013-01-10 at 4.03.53 PM

There are a lot of data points available, but you need to know where to look.  At first look, it may seem like late-stage investments are safer bets than  early-stage investments. But looking back over the previous decade, we  discovered in our research that the risk of failure is about the same! A 49  percent failure rate in early rounds yielded a 2.8x money multiple versus a 45  percent failure rate and 1.3x multiple in later-stage rounds.

Traditional investors claim that the key to success is finding the next  Zuckerberg. In my view, this is the very reason why traditional VC firms fail to  deliver results. It shouldn’t be about discovering the next Facebook. It’s about  positioning yourself to find it. You don’t do that by swinging hard every single  time. Look at any legendary investor, Warren Buffett for instance, and you’ll  see that they don’t swing at every ball, but rather follow mathematical  investment models that incorporate appropriate factors of safety.

The claim that VC’s need to rely on old school-hustle, homework, and instinct  is also simply wrong because the VC’s that follow this mindset couldn’t deliver  sufficient returns, and are struggling to raise their next funds.

Let’s get into a little more detail. There are three key activities in  venture investing: Deciding which startup(s) to invest in, how much to invest,  and how to construct the portfolio.

Using decision models, and some of these models have been widely-used over  the last 20 years in a number of areas such as medicine and engineering, we  can:

  • Establish a bias-free, data driven selection model.
  • Optimize investment sizes per company.
  • Optimize investment portfolio of companies.

Without revealing too much about our research, I can say that we use  proprietary variations of models already used elsewhere, such as Multiple  Criteria Decision Analysis (MCDA), Kelly Criterion, and the Markowitz portfolio  theory. These theories must be modified for the characteristics of the venture  capital business, and we’ve attempted to do that, and filed patents on them  while we were at it. Our MCDA matrix has elements similar to those used in the “Startup Genome” project.

The “Moneyball” approach to venture capital forces us to work harder and  smarter to overcome the cognitive limitations instead of “the best gut-feeling  pickers.” Traditional VC takes way too much credit for successes, and doesn’t  accept its failures.

We should look at successes and failures as data points to improve our math  to get to our goal: to deliver superior returns to our limited partners.

Matt-OguzMatt  Oguz is a founding partner of Palo Alto Venture Science, a firm that brings a  data-driven approach to VC. He has been an angel investor in early-stage  startups since 2005, and specializes in e-commerce, analytics, behavioral  economics and decision sciences.

Prior to this, he built big data solutions for a number of Fortune  500 companies such as Dow Corning, Coca Cola and General Electric.


Wipe-On Nanocoating to Exceed Automotive OEM Specs

QDOTS imagesCAKXSY1K 8(Nanowerk News) Imagine for a moment a world were  automotive plastics never fade, a self-cleaning wheel that resists brake dust, a  self-cleaning tire that looks new for life, or a fiberglass boat that resists  fading for life. These and other amazing benefits are now possible due to 10  years of research & development in nanotechnology.
According to Nanovere Technologies Chairman & Chief  Technology Officer Thomas Choate, “Nanovere is pleased to introduce the world’s  first Wipe-On clear nanocoating to exceed automotive OEM specifications. The  product is named Vecdor Nano-Clear®. What’s most unique about Nano-Clear® is the  ability to permanently restore original color, gloss and surface hardness back  into oxidized textured plastics, highly oxidized fiberglass and highly oxidized  paint surfaces while reducing surface maintenance by 60%.”
Nanotechnology can be described as the science of molecular  engineering. Nanovere Technologies has pioneered proprietary 3D nanostructured  coatings at the molecular level since 2003. Nano-Clear® forms a “highly  crosslink dense film with extreme scratch resistance, chemical resistance, UV  resistance, remarkable flexibility and self-cleaning properties including water,  oil, ice and brake-dust repellency.”
The application potential for Nano-Clear® Wipe-On nanocoating  includes automotive textured plastics, aluminum and steel wheels, tires,  oxidized paint surfaces including heavy duty equipment, boat hulls, aluminum  siding, outdoor metal furniture, air conditioner housings, etc.
Vecdor nanocoatings have been tested and validated by some of  the world’s leading OEM companies including Boeing, BMW, Accuride Truck Wheels  and many others to outperform leading OEM clear coatings;
  • 53%  higher scratch resistance: 4H pencil hardness
  • 476%  higher chemical resistance over nearest competitor: 500+ MEK rubs
  • 60%  reduced surface maintenance: water, oil and ice repellency
  • 94%  gloss retention even after 5 years
Nanovere is currently establishing global distribution networks  for Vecdor Nano-Clear®. Interested parties may contact Nanovere directly at or call us at  (810)  227-0077 . To learn  more about Nanovere or nanotechnology, please visit us at or email                    
Nanovere Technologies, LLC. specializes in the research &  development of first-to-market nanocoatings and licensing of 3D nanostructured  coating polymers to a world leading paint manufacture. Nanovere Technologies was  founded in 2003 and invented the core polymers and nanocoatings which currently  represent 11 global patents pending.
Source: Nanovere (press  release)

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Improved nanoparticles deliver drugs into brain

Written by Hopkins CCNE    Friday, 09 November 2012 09:12
Researchers report they are one step closer to a drug-delivery system flexible enough to overcome some key challenges posed by brain cancer and other maladies affecting the brain.

In a report published in Science Translational Medicine, a team of researchers from Johns Hopkins says it has designed nanoparticles that can safely and predictably infiltrate deep into the brain when tested in rodent and human tissue. “We are pleased to have found a way to prevent drug-embedded particles from sticking to their surroundings so that they can spread once they are in the brain,” says Justin Hanes, a project leader at the Hopkins CCNE and director of the Johns Hopkins Center for Nanomedicine.

After surgery to remove a brain tumor, standard treatment protocols include the administering chemotherapy directly to the surgical site to kill any cells left behind that could not be surgically removed. To date, this method of preventing tumor recurrence is only moderately successful, in part because it is hard to administer a dose of chemotherapy high enough to sufficiently penetrate the tissue to be effective and low enough to be safe for the patient and healthy tissue.

To overcome this dosage challenge, Dr. Hanes and his colleagues designed nanoparticles that are able to travel faster and further into the brain tissue. While conventional drug-delivery nanoparticles typically stick to cells at the application site and tend to not migrate deeper into the brain, these new nanoparticles, coated with a dense layer of poly(ethylene glycol (PEG)interact minimally with the surrounding tissue and are more able to move out from the injection site.

To test the performance of their slippery nanoparticles, Dr. Hanes and his colleagues injected the coated beads into slices of rodent and human brain tissue. They first labeled the beads with glowing tags that enabled them to see the beads as they moved through the tissue. Compared to non-PEG-coated beads, or beads with a less dense PEG coating, they found that a dense coating of PEG allowed larger beads to penetrate the tissue, even those beads that were nearly twice the size previously thought to be the maximum possible for penetration within the brain. They then tested these beads in live rodent brains and found the same results.

The researchers then took biodegradable nanoparticles carrying the chemotherapy drug paclitaxel, and coated them with PEG. As expected, in rat brain tissue, nanoparticles without the PEG coating moved very little, while PEG-covered nanoparticles distributed themselves quite well.

This work, which is detailed in a paper titled, “A dense poly(ethylene glycol) coating improves penetration of large polymeric nanoparticles within brain tissue,” was supported in part by the NCI Alliance for Nanotechnology in Cancer, a comprehensive initiative designed to accelerate the application of nanotechnology to the prevention, diagnosis, and treatment of cancer. An abstract of this paper is available at the journal’s website.


Nanoclays lead to better asphalt in roads.


Long before the age of freeways and parking lots, Babylonians used a naturally occurring asphalt to reinforce their roads. You can still see patches of the old pavement in the ancient city, even though it was installed in about 600 B.C. Under the onslaught of 21st century traffic, modern asphalt isn’t likely to hold up for anywhere near 2,700 years. But at Michigan Technological University, Zhanping You is paving the way for brand-new asphalt blends to fight off cracks, rutting and potholes.


His work has drawn so much attention that one of his papers made SciVerse ScienceDirect’s Top 25 Hottest Articles of 2011 for the journal Construction and Building Materials. “Nanoclay-Modified Asphalt Materials: Preparation and Characterization” reviews recent literature on asphalt that has been doctored with nanomaterials. It also presents new discoveries from You’s team suggesting that adding nanoclays to asphalt materials could make for safer, longer-lasting roadways.

“Asphalt is now made from petroleum, so it’s very expensive,” said You, an associate professor of civil and environmental engineering. “As a result, a lot of people are looking at ways to make it more durable.” Heat, cold and stress in the form of traffic take their toll on asphalt pavement, made from a mix of asphalt and aggregates like gravel. That leads to cracks, potholes and a process called rutting. Ruts are most likely to form on busy roads, sections with slow traffic, and areas with stop signs and stoplights, where the rubber hits the road hard thousands of times a day.

“Rutting can be very dangerous, especially in snow and ice,” You said. “If we could use advanced materials to reduce rutting, that would be very beneficial to the public.” You’s team tested two types of nanoclays, adding 2–4 percent by weight to the asphalt. That’s a smidgeon–less than half of a percent of the total weight of the asphalt pavement itself. But it made a big difference.

“It improved the viscosity significantly,” You said. “That means it will provide better stiffness, which means that it won’t deform as much in hot weather or under heavy traffic.” They don’t yet know if nanoclay can help asphalt resist cracking in cold weather or under heavy loads, since their testing isn’t completed. “But it is always our goal to develop new asphalt mixtures with those qualities,” You said. His lab is also testing how other nanomaterials, including nano-silica and nano-composites, will affect asphalt durability.

In addition to You, coauthors of “Nanoclay-Modified Asphalt Materials: Preparation and Characterization” are Assistant Professor Qingli Dai, PhD students Julian Mills-Beale and Shu Wei Goh and former undergraduate Justin Foley of Michigan Tech’s Department of Civil and Environmental Engineering; Samit Roy of the University of Alabama, Tuscaloosa; and Associate Professor Gregory Odegard of Michigan Tech’s Department of Mechanical Engineering-Engineering Mechanics.

Leadership Secret Three: Two Skills Great Leaders Master

Leaders have the quality of emotional mastery, which gives you the strength and flexibility to tackle any challenge, even when all hell is breaking loose, as we covered in the previous blog post in this series. Now we’ll look at two other core qualities extraordinary leaders possess, RELATIONSHIP MASTERY and TIME MASTERY.


Ultimately the quality of your life is the quality of your relationships. How many times have you heard, “business is relationship?”  It’s one of those clichés that never escapes us. But one reason we hear clichés again and again is because they are true. Ultimately our capacity to connect, not on a surface level, but on a very deep and personal level, is what allows us to break through the limitations that stop ourselves or any individual or group we are looking to lead to a new level.

Relationships are built not just by practicing rapport skills, but by truly understanding and appreciating where people are coming from—wanting to step in their shoes, understanding their point of view and finding a way to help them meet their needs while they meet the needs of the team and the organization. Facebook and Twitter are great tools, but if your idea of friendship is your Facebook or Twitter circles, perhaps it’s time to look deeper.

How well would you rate your own capacity to go deep in relationships, to penetrate beyond the surface of what people tell you to find out what’s really going on so that you can help people and yourself take things to a new level as a leader?





I don’t have to tell you, in the 24/7 LinkedIn, Twitter, Facebook, Google+ mobile world that we live in today that the mastery of time—learning how to extract greater results from the same hours or minutes—is one of the most important skill sets of any great leader. But truly effective leaders learn not only how to get more out of their time, but they teach others to do the same. It’s so easy to get caught up today in activity and mistake movement for achievement. Every great leader I know learns how to cut through the clutter of to-dos to focus on how to get the results that are necessary more rapidly, more efficiently, and more effectively. For most people today, we’re not hurting for information. We’re drowning in information, but we’re starving for wisdom.

On a weekly basis, the average executive receives more than 500 emails, sits in an average of 14 meetings, receives over 200 inbound phone calls, and is out of the office 65% of the time.  That’s not even considering the impact of text messaging and social media. And still they have to figure out how to produce results.

We have more tools than ever before, but very often the tools themselves can become a time thief. The test of leadership is not only getting things done, but often times the greatest reason for failure is good people doing the right thing, at the wrong time. A simple example from our recent economy might be buying a house. It was the right thing to do, but if you did it in 2006 or 2007 it was the wrong time and today you are probably upside down 30-50%. Great leaders are constantly refining their capacity to understand what’s most important to be done and when to get it done to produce the greatest impact.

How would you rate your capacity and your mastery of time, 0 to 10, and what could you do to improve it? This is such an important subject and will be the focus of a future blog.